Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SARS-CoV-2-IN-60 (compound 5a) is a specific, irreversible inhibitor of SARS-CoV-2 nsp16-nsp10 methyltransferase, competing with S-adenosylmethionine (SAM) and exhibiting an IC50 of 9 µM and a Ki of 26 µM. It binds to a novel pocket near the SAM-binding site on nsp16, suggesting potential as a pan-coronavirus therapeutic [1].
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Description | SARS-CoV-2-IN-60 (compound 5a) is a specific, irreversible inhibitor of SARS-CoV-2 nsp16-nsp10 methyltransferase, competing with S-adenosylmethionine (SAM) and exhibiting an IC50 of 9 µM and a Ki of 26 µM. It binds to a novel pocket near the SAM-binding site on nsp16, suggesting potential as a pan-coronavirus therapeutic [1]. |
Molecular Weight | 335.11 |
Formula | C13H7Cl2F3N2O |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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SARS-CoV-2-IN-60 Microbiology/Virology SARS-CoV inhibitor inhibit