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Anti-C1D Antibody (4C458) is a Rabbit antibody targeting C1D. Anti-C1D Antibody (4C458) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-C1D Antibody (4C458) is a Rabbit antibody targeting C1D. Anti-C1D Antibody (4C458) can be used in ELISA. |
Alias | SUN-CoR, SUNCOR, Rrp47, LRP1, hC1D, C1D nuclear receptor corepressor |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4C458 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human C1D (rh C1D; TMPY-02883; Q13901; Met1-Ser141). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressorcan activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human C1D protein (TMPY-02883) |
Antigen Species | Human |
Biology Area | Apoptosis Transcription Factors and Regulators |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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