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Anti-HER3/ERBB3 Antibody (6V625)
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Catalog No. TMAH-00403
Alias p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ErbB3
Anti-HER3/ERBB3 Antibody (6V625) is an antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (6V625) can be used in ELISA, IF.
Anti-HER3/ERBB3 Antibody (6V625)
Anti-HER3/ERBB3 Antibody (6V625)
😃Good
Catalog No. TMAH-00403Alias p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ErbB3
Anti-HER3/ERBB3 Antibody (6V625) is an antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (6V625) can be used in ELISA, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Chemical Properties
| Description | Anti-HER3/ERBB3 Antibody (6V625) is an antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (6V625) can be used in ELISA, IF. |
| Alias | p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ErbB3 |
| Ig Type | Rabbit IgG |
| Clone | 6V625 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of MCF7 Cells with TMAH-00403 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
| Application | ELISA, IF |
| Recommended Dose | IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ErbB3 |
| Antigen Species | Human |
| Gene ID | 2065 |
| Uniprot ID | |
| Biology Area | Cancer, Tags & Cell Markers, Signal transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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