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ODM-207

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Catalog No. T10521Cas No. 1801503-93-4
Alias ODM207, BET-IN-4

ODM-207 (BET-IN-4) is a potent inhibitor of BRD4.

ODM-207

ODM-207

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Purity: 99.75%
Catalog No. T10521Alias ODM207, BET-IN-4Cas No. 1801503-93-4
ODM-207 (BET-IN-4) is a potent inhibitor of BRD4.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$39In StockIn Stock
5 mg$88In StockIn Stock
10 mg$143In StockIn Stock
25 mg$262In StockIn Stock
50 mg$377In StockIn Stock
100 mg$533In StockIn Stock
200 mg$733-In Stock
1 mL x 10 mM (in DMSO)$97In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.75%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
ODM-207 (BET-IN-4) is a potent inhibitor of BRD4.
Targets&IC50
BRD4:1 μM
In vitro
BET-IN-4 inhibits BRD4 with an IC50 of ≤ 1 μM[1].
SynonymsODM207, BET-IN-4
Chemical Properties
Molecular Weight375.42
FormulaC22H21N3O3
Cas No.1801503-93-4
SmilesCOc1cc2n(Cc3ccccn3)c(=O)c(C)cc2cc1-c1c(C)noc1C
Relative Density.1.232 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5 mg/mL (13.32 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6637 mL13.3184 mL26.6368 mL133.1842 mL
5 mM0.5327 mL2.6637 mL5.3274 mL26.6368 mL
10 mM0.2664 mL1.3318 mL2.6637 mL13.3184 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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