Isogentisin

Name: Isogentisin
Brand: TargetMol
SKU: T32208
Rating: 4.5 (1 reviews)

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Catalog No. T32208Cas No. 491-64-5

Alias BRN-0258402, BRN0258402, BRN 0258402

Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase.

Isogentisin

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Catalog No. T32208Alias BRN-0258402, BRN0258402, BRN 0258402Cas No. 491-64-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	Backorder	Backorder
5 mg	$430	Backorder	Backorder
10 mg	$640	Backorder	Backorder
25 mg	$1,110	Backorder	Backorder
50 mg	$1,690	Backorder	Backorder
100 mg	$2,620	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase.
In vitro	The G. lutea leaf extract exhibited moderate cytotoxic effects toward HeLa cells with an IC50 value of 41.1 microg/mL. Isogenisin was isolated and identified from G. lutea leaves, isogentisin exerted strong activity against HeLa cells, with IC50 values is 8.8 ± 0.9 μg/mL.[1]
Synonyms	BRN-0258402, BRN0258402, BRN 0258402

Chemical Properties

Molecular Weight	258.2262
Formula	C₁₄H₁₀O₅
Cas No.	491-64-5
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc