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1-Stearoyl-rac-glycerol

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Catalog No. T36454Cas No. 123-94-4
Alias Monostearin, Glyceryl monostearate

1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenesis. 1-Stearoyl-rac-glycerol has been used in the composition of transfersomes for transdermal delivery of doxorubicin in rats, leading to doxorubicin accumulation in lymph nodes, spleen, and heart.

1-Stearoyl-rac-glycerol

1-Stearoyl-rac-glycerol

😃Good
Catalog No. T36454Alias Monostearin, Glyceryl monostearateCas No. 123-94-4
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenesis. 1-Stearoyl-rac-glycerol has been used in the composition of transfersomes for transdermal delivery of doxorubicin in rats, leading to doxorubicin accumulation in lymph nodes, spleen, and heart.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30-In Stock
50 mg$73-In Stock
100 mg$118-In Stock
500 mg$293-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenesis. 1-Stearoyl-rac-glycerol has been used in the composition of transfersomes for transdermal delivery of doxorubicin in rats, leading to doxorubicin accumulation in lymph nodes, spleen, and heart.
SynonymsMonostearin, Glyceryl monostearate
Chemical Properties
Molecular Weight358.56
FormulaC21H42O4
Cas No.123-94-4
SmilesCCCCCCCCCCCCCCCCCC(=O)OCC(O)CO
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Chloroform: 50 mg/mL (139.45 mM), Sonication is recommended.
DMSO: 10 mg/mL (27.89 mM), Sonication and heating is recommended.
Solution Preparation Table
DMSO/Chloroform
1mg5mg10mg50mg
1 mM2.7889 mL13.9447 mL27.8893 mL139.4467 mL
5 mM0.5578 mL2.7889 mL5.5779 mL27.8893 mL
10 mM0.2789 mL1.3945 mL2.7889 mL13.9447 mL
20 mM0.1394 mL0.6972 mL1.3945 mL6.9723 mL
Chloroform
1mg5mg10mg50mg
50 mM0.0558 mL0.2789 mL0.5578 mL2.7889 mL
100 mM0.0279 mL0.1394 mL0.2789 mL1.3945 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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