Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3, and 1.95 nM for TYK2. It effectively reduces joint swelling while maintaining a good safety profile [1].
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Description | JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3, and 1.95 nM for TYK2. It effectively reduces joint swelling while maintaining a good safety profile [1]. |
Molecular Weight | 450.53 |
Formula | C27H26N6O |
CAS No. | 2068766-90-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JAK-IN-34 2068766-90-3 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells JAK inhibitor inhibit