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1,5-Anhydrosorbitol

Name: 1,5-Anhydrosorbitol
Brand: TargetMol
SKU: TQ0195
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TQ0195Cas No. 154-58-5

1,5-Anhydrosorbitol is a validated marker of short-term glycemic control. This substance is derived mainly from food.

1,5-Anhydrosorbitol

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Purity: 99.66%

Catalog No. TQ0195Cas No. 154-58-5

1,5-Anhydrosorbitol is a validated marker of short-term glycemic control. This substance is derived mainly from food.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$44	In Stock	In Stock
25 mg	$85	In Stock	In Stock
50 mg	$139	In Stock	In Stock
100 mg	$198	In Stock	In Stock
200 mg	$297	-	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.66%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

1,5-Anhydrosorbitol AI Summary

1,5-Anhydrosorbitol exhibits bioactivities related to antiviral, cytotoxic, and enzyme interaction properties. It demonstrates a concentration of 5000.0 uM that protects by 50% the cytopathic effect induced by herpes simplex virus-1 and induces 50% cell toxicity in monolayers of uninfected HeLa cells at the same concentration. Additionally, 1,5-Anhydrosorbitol shows binding affinity towards sweet almond Beta-glucosidase and E. coli Beta-galactosidase and exhibits Michaelis-Menten constants against these enzymes, indicating potential specificity in activity. The compound also shows kinetic parameters Km/Kcat against Beta-glucosidase, further highlighting its potential role in enzyme modulation..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

1,5-Anhydrosorbitol is a validated marker of short-term glycemic control. This substance is derived mainly from food.

Chemical Properties

Molecular Weight	164.16
Formula	C₆H₁₂O₅
Cas No.	154-58-5
Smiles	OC[C@H]1OC[C@H](O)[C@@H](O)[C@@H]1O
Relative Density.	1.533 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 138.9 mg/mL (846.13 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0916 mL	30.4581 mL	60.9162 mL	304.5809 mL
5 mM	1.2183 mL	6.0916 mL	12.1832 mL	60.9162 mL
10 mM	0.6092 mL	3.0458 mL	6.0916 mL	30.4581 mL
20 mM	0.3046 mL	1.5229 mL	3.0458 mL	15.2290 mL
50 mM	0.1218 mL	0.6092 mL	1.2183 mL	6.0916 mL
100 mM	0.0609 mL	0.3046 mL	0.6092 mL	3.0458 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc