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Anti-BOLA1 Antibody (2Q815)

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Catalog No. TMAY-02624
Alias CGI-143, bolA family member 1

Anti-BOLA1 Antibody (2Q815) is a Rabbit antibody targeting BOLA1. Anti-BOLA1 Antibody (2Q815) can be used in ELISA.

Anti-BOLA1 Antibody (2Q815)

Anti-BOLA1 Antibody (2Q815)

😃Good
Catalog No. TMAY-02624Alias CGI-143, bolA family member 1
Anti-BOLA1 Antibody (2Q815) is a Rabbit antibody targeting BOLA1. Anti-BOLA1 Antibody (2Q815) can be used in ELISA.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-BOLA1 Antibody (2Q815) is a Rabbit antibody targeting BOLA1. Anti-BOLA1 Antibody (2Q815) can be used in ELISA.
AliasCGI-143, bolA family member 1
Ig Type
Monoclonal Rabbit IgG
Clone
2Q815
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human BOLA1/hBolA (rh BOLA1/hBolA; TMPY-04022; Q9Y3E2; Met1-Pro137).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundBOLA1 is a mitochondrial protein that counterbalances the effect of L-buthionine-(S,R)-sulfoximine (BSO)-induced glutathione (GSH) depletion on the mitochondrial thiol redox potential. Furthermore, overexpression of BOLA1 nullifies the effect of BSO and S-nitrosocysteine on mitochondrial morphology. Conversely, knockdown of the BOLA1 gene increases the oxidation of mitochondrial thiol groups. Supporting a role of BOLA1 in controlling the mitochondrial thiol redox potential is that BOLA1 orthologs only occur in aerobic eukaryotes. A measured interaction of BOLA1with the mitochondrial monothiol glutaredoxin GLRX5 provides hints for potential mechanisms behind BOLA1's effect on mitochondrial redox potential.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human BOLA1/hBolA Protein (TMPY-04022)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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