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RAD51-IN-1

🥰Excellent
Catalog No. T9271Cas No. 2101739-18-6

Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.

RAD51-IN-1

RAD51-IN-1

🥰Excellent
Purity: 99.95%
Catalog No. T9271Cas No. 2101739-18-6
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$34In StockIn Stock
5 mg$55In StockIn Stock
10 mg$89In StockIn Stock
25 mg$178In StockIn Stock
50 mg$297In StockIn Stock
100 mg$478In StockIn Stock
1 mL x 10 mM (in DMSO)$61In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.95%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
In vitro
RAD51-IN-1(10μM) decreases the ratio of RAD51 positive cells/cH2AX postive cells in MDA-MB-231 cell exposure to 6 Gy irradiation. RAD51-IN-1 (10μM) significantly inhibits DNA damage induced RAD51 foci formation with 6 Gy irradiation.[1]
Chemical Properties
Molecular Weight373.83
FormulaC22H16ClN3O
Cas No.2101739-18-6
SmilesClc1ccc(Cn2c(\C=C\c3cccnc3)nc3ccccc3c2=O)cc1
Relative Density.1.24 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (73.56 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.35 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6750 mL13.3751 mL26.7501 mL133.7506 mL
5 mM0.5350 mL2.6750 mL5.3500 mL26.7501 mL
10 mM0.2675 mL1.3375 mL2.6750 mL13.3751 mL
20 mM0.1338 mL0.6688 mL1.3375 mL6.6875 mL
50 mM0.0535 mL0.2675 mL0.5350 mL2.6750 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

tumor cellRNASynthesisRNA SynthesisRAD51-IN-1RAD-51-IN-1RAD51IN1RAD51 IN 1RAD51InhibitorinhibitDNASynthesisDNA SynthesisDNA damagechemotherapycancer
Related Tags: buy RAD51-IN-1 | purchase RAD51-IN-1 | RAD51-IN-1 cost | order RAD51-IN-1 | RAD51-IN-1 chemical structure | RAD51-IN-1 in vitro | RAD51-IN-1 formula | RAD51-IN-1 molecular weight
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