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5-hydroxy Indomethacin

Name: 5-hydroxy Indomethacin
Brand: TargetMol
SKU: T37210
Rating: 4.5 (1 reviews)

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Catalog No. T37210Cas No. 2504-32-7

5-hydroxy Indomethacin is a metabolite of indomethacin .1It is formed from indomethacin in rabbit hepatic microsomes.

5-hydroxy Indomethacin

😃Good

Catalog No. T37210Cas No. 2504-32-7

5-hydroxy Indomethacin is a metabolite of indomethacin .1It is formed from indomethacin in rabbit hepatic microsomes.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$155	35 days	35 days
10 mg	$288	35 days	35 days
25 mg	$485	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

5-hydroxy Indomethacin is a metabolite of indomethacin .1It is formed from indomethacin in rabbit hepatic microsomes.

Chemical Properties

Molecular Weight	343.76
Formula	C₁₈H₁₄ClNO₄
Cas No.	2504-32-7
Smiles	Cc1c(CC(O)=O)c2cc(O)ccc2n1C(=O)c1ccc(Cl)cc1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 30 mg/mL (87.27 mM), Sonication is recommended.

DMSO: 15 mg/mL (43.64 mM), Sonication is recommended.

Ethanol: 3 mg/mL (8.73 mM), Sonication is recommended.

PBS (pH 7.2): Insouble

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.9090 mL	14.5450 mL	29.0901 mL	145.4503 mL
5 mM	0.5818 mL	2.9090 mL	5.8180 mL	29.0901 mL

DMSO/DMF

	1mg	5mg	10mg	50mg
10 mM	0.2909 mL	1.4545 mL	2.9090 mL	14.5450 mL
20 mM	0.1455 mL	0.7273 mL	1.4545 mL	7.2725 mL

DMF

	1mg	5mg	10mg	50mg
50 mM	0.0582 mL	0.2909 mL	0.5818 mL	2.9090 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc