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Lacnotuzumab (Synonyms: MCS110, MCS 110, Anti-Human B7-H3)

Catalog No. T76868 Copy Product Info
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Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, inhibiting the macrophage colony-stimulating factor pathway upstream components, used in retinal disease research.

Lacnotuzumab

Copy Product Info
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Catalog No. T76868
Synonyms MCS110, MCS 110, Anti-Human B7-H3

Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, inhibiting the macrophage colony-stimulating factor pathway upstream components, used in retinal disease research.

Lacnotuzumab
Cas No. 1831128-32-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$328In StockIn Stock
5 mg$1,160In StockIn Stock
10 mg$1,860-In Stock
25 mg$2,770-In Stock
50 mg$3,730-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Purity:99.36% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, inhibiting the macrophage colony-stimulating factor pathway upstream components, used in retinal disease research.
In vivo
Treatment of NOD/SCID mice with anti-human CSF-1 mAb Lacnotuzumab by subcutaneous injection of CHLA-255-Fluc NBs (given alone once weekly) reduced human monocyte-derived CD163 + cells but did not improve chemotherapy. [2]
SynonymsMCS110, MCS 110, Anti-Human B7-H3
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCSF1/M-CSF
Chemical Properties
Molecular Weight144.8 kDa
Cas No.1831128-32-5
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature | Shipping with blue ice/Shipping at ambient temperature.

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