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Anti-IL-1 beta Antibody (3E298)
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Catalog No. TMAY-01258
Anti-IL-1 beta Antibody (3E298) is a Mouse antibody targeting IL-1 beta. Anti-IL-1 beta Antibody (3E298) can be used in WB.
Anti-IL-1 beta Antibody (3E298)
Anti-IL-1 beta Antibody (3E298)
😃Good
Catalog No. TMAY-01258
Anti-IL-1 beta Antibody (3E298) is a Mouse antibody targeting IL-1 beta. Anti-IL-1 beta Antibody (3E298) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Mouse Monoclonal Application: WB Reactivity: Human |
| Ig Type | Mouse IgG2b |
| Clone | 3E298 |
| Reactivity | Human |
| Verified Activity | Anti-IL-1 beta mouse monoclonal antibody at 1:500 dilution. -Lane A: Untreated THP1 Whole Cell Lysate. -Lane B: THP-1 cells differentiated with TPA(80 nM,overnight) followed by treatment with LPS(1 μg/ml ,8h). -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:31 kDa. -Observed band size: kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: center region of the Human IL-1 beta |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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