Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values of 0.05 nM for CBP and 0.2 nM for p300. The compound comprises lenalidomide (the cereblon ligand), a connecting linker, and GNE-207 (the bromodomain inhibitor). JET-209 is utilized in cancer research [1].
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values of 0.05 nM for CBP and 0.2 nM for p300. The compound comprises lenalidomide (the cereblon ligand), a connecting linker, and GNE-207 (the bromodomain inhibitor). JET-209 is utilized in cancer research [1]. |
Molecular Weight | 821.92 |
Formula | C46H47N9O6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JET-209 PROTAC PROTACs inhibitor inhibit