This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
HDAC/BET-IN-1
Catalog No. T72872 CAS
2757573-68-3
HDAC/BET-IN-1 is a chemical compound exhibiting submicromolar inhibitory activity against HDAC1 and HDAC6, with IC50 values of 0.163 μM and 0.067 μM, respectively, and against BRD4, with a Ki of 0.076 μM. Additionally, it possesses potent antileukemia activity.
All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage
& Solubility Information
Description
HDAC/BET-IN-1 is a chemical compound exhibiting submicromolar inhibitory activity against HDAC1 and HDAC6, with IC50 values of 0.163 μM and 0.067 μM, respectively, and against BRD4, with a Ki of 0.076 μM. Additionally, it possesses potent antileukemia activity.
Molecular Weight
604.71
Formula
C29H40N4O8S
CAS No.
2757573-68-3
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Method for preparing DMSO master liquid: mg
drug pre-dissolved in μL DMSO (Master liquid concentration
mg/mL),
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL PEG300, mix and clarify, next add μL
Tween 80,mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL Corn oil,mix and clarify.
Note:
Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.