Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.
Description | Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM. |
Molecular Weight | 349.27 |
Formula | C14H18Cl2N2O2S |
CAS No. | 78957-84-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Calmodulin antagonist-1 78957-84-3 Calmodulin antagonist 1 Calmodulin antagonist1 inhibitor inhibit