Sterigmatocystine

Name: Sterigmatocystine
Brand: TargetMol
SKU: T16942
Rating: 4.5 (1 reviews)

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Catalog No. T16942Cas No. 10048-13-2

Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.

Sterigmatocystine

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Catalog No. T16942Cas No. 10048-13-2

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$364	35 days	35 days
10 mg	Inquiry	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
In vitro	Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, leading to G2 arrest in GES-1 cells [4].
In vivo	Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) suppresses p21WAF1/CIP1 [3].

Chemical Properties

Molecular Weight	324.28
Formula	C₁₈H₁₂O₆
Cas No.	10048-13-2
Relative Density.	1.51 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc