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Anti-CXCL1 Antibody (2U261)
😃Good
Catalog No. TMAY-01273
Alias SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H
Anti-CXCL1 Antibody (2U261) is a Mouse antibody targeting CXCL1. Anti-CXCL1 Antibody (2U261) can be used in ELISA(Det).
Anti-CXCL1 Antibody (2U261)
Anti-CXCL1 Antibody (2U261)
😃Good
Catalog No. TMAY-01273Alias SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H
Anti-CXCL1 Antibody (2U261) is a Mouse antibody targeting CXCL1. Anti-CXCL1 Antibody (2U261) can be used in ELISA(Det).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $69 | 7-10 days | 7-10 days | |
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CXCL1 Antibody (2U261) is a Mouse antibody targeting CXCL1. Anti-CXCL1 Antibody (2U261) can be used in ELISA(Det). |
| Synonyms | SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H |
| Ig Type | Mouse IgG2a |
| Clone | 2U261 |
| Reactivity | Human |
| Specificity | Human CXCL1 |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CXCL1 (rh CXCL1; TMPY-02868; P09341-1; Ala35-Asn107). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized roles in angiogenesis and inflammation. CXCL1 is a novel immediate PTH/PTHrP-responsive gene. CXCL1 may act as a chemoattractant for osteoclast precursors. CXCL1 may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection. CXCL1 functions through CXCR2 to transactivate the EGFR by proteolytic cleavage of HB-EGF, leading to activation of MAPK signalling and increased proliferation of epithelial ovarian cancer (EOC) cells. It might limit tumor growth by reinforcing senescence early in tumorigenesis. Thus, CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CXCL1 Protein (TMPY-02868) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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