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(-)-Salutaridine

Name: (-)-Salutaridine
Brand: TargetMol
SKU: T5760
Price: 84 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5760Cas No. 4090-18-0

Alias SINOACUTINE

(-)-Salutaridine is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.

(-)-Salutaridine

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Purity: 99.99%

Catalog No. T5760Alias SINOACUTINECas No. 4090-18-0

(-)-Salutaridine is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$84	In Stock	In Stock
10 mg	$140	In Stock	In Stock
25 mg	$252	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.99%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

(-)-Salutaridine AI Summary

(-)-Salutaridine has vasorelaxation activity as it inhibits phenylephrine-induced contraction in Sprague-Dawley rat aortic tissues with an IC50 value of 32800.0 nM. The compound also exhibits cytotoxic activity against human HepG2 cells and human HepG2(2.2.15) cells, with IC50 values of 10.2 ug/mL and 10.4 ug/mL, respectively. Additionally, (-)-Salutaridine demonstrates antimalarial activity against both chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum, with an effective dose (ED50) for antimalarial activity being greater than 10,000.0 ng/mL after 24 hours..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	(-)-Salutaridine is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.
Synonyms	SINOACUTINE

Chemical Properties

Molecular Weight	327.37
Formula	C₁₉H₂₁NO₄
Cas No.	4090-18-0
Smiles	OC1=C2[C@]34C([C@](CC2=CC=C1OC)(N(C)CC3)[H])=CC(=O)C(OC)=C4
Relative Density.	1.33 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (183.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0546 mL	15.2732 mL	30.5465 mL	152.7324 mL
5 mM	0.6109 mL	3.0546 mL	6.1093 mL	30.5465 mL
10 mM	0.3055 mL	1.5273 mL	3.0546 mL	15.2732 mL
20 mM	0.1527 mL	0.7637 mL	1.5273 mL	7.6366 mL
50 mM	0.0611 mL	0.3055 mL	0.6109 mL	3.0546 mL
100 mM	0.0305 mL	0.1527 mL	0.3055 mL	1.5273 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc