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CK1-IN-3

Name: CK1-IN-3
Brand: TargetMol
SKU: T60005
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60005Cas No. 349438-74-0

CK1-IN-3 is casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention of diseases associated with circadiantiazol rhythm, inflammation diseases.

CK1-IN-3

🥰Excellent

Purity: 99.18%

Catalog No. T60005Cas No. 349438-74-0

CK1-IN-3 is casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention of diseases associated with circadiantiazol rhythm, inflammation diseases.

Pack Size	Price	Availability
1 mg	$30	In Stock
5 mg	$68	In Stock
10 mg	$103	In Stock
25 mg	$188	In Stock
50 mg	$271	In Stock
100 mg	$372	In Stock
200 mg	$510	In Stock
1 mL x 10 mM (in DMSO)	$75	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.18%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	CK1-IN-3 is casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention of diseases associated with circadiantiazol rhythm, inflammation diseases.
Targets&IC50	CK1δ:2.22 μM

Chemical Properties

Molecular Weight	328.39
Formula	C₁₇H₁₆N₂O₃S
Cas No.	349438-74-0
Smiles	N(C(CC1=C(OC)C=CC=C1)=O)C2=NC=3C(S2)=CC(OC)=CC3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (152.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0452 mL	15.2258 mL	30.4516 mL	152.2580 mL
5 mM	0.6090 mL	3.0452 mL	6.0903 mL	30.4516 mL
10 mM	0.3045 mL	1.5226 mL	3.0452 mL	15.2258 mL
20 mM	0.1523 mL	0.7613 mL	1.5226 mL	7.6129 mL
50 mM	0.0609 mL	0.3045 mL	0.6090 mL	3.0452 mL
100 mM	0.0305 mL	0.1523 mL	0.3045 mL	1.5226 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc