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Chloroallyl methenamine chloride

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Catalog No. T77505Cas No. 51229-78-8
Alias Quaternium-15 cis-form

cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (Quaternium-15 cis-form) is an antimicrobial agent used in cosmetics as a cosmetic preservative and antistatic agent.cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride is an oral teratogen, but not a dermal teratogen, and has been dosed in rats at doses exceeding the expected cumulative exposures for cosmetics.

Chloroallyl methenamine chloride

Chloroallyl methenamine chloride

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🥰Excellent
Purity: 99.95%
Catalog No. T77505Alias Quaternium-15 cis-formCas No. 51229-78-8
cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (Quaternium-15 cis-form) is an antimicrobial agent used in cosmetics as a cosmetic preservative and antistatic agent.cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride is an oral teratogen, but not a dermal teratogen, and has been dosed in rats at doses exceeding the expected cumulative exposures for cosmetics.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$34In StockIn Stock
1 g$48In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.95%
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Product Introduction

Chloroallyl methenamine chloride AI Summary
Chloroallyl methenamine chloride exhibits antiviral activity against SARS-CoV-2 by inhibiting virus-induced cytotoxicity and shows potential for inhibiting the SARS-CoV-2 3CL-Pro protease. High content imaging assays indicate that at a concentration of 10 µM, the compound inhibited cytotoxicity in Caco-2 cells by -7.47% and in VERO-6 cells by 0.09% after 48 hours of exposure. Additionally, the compound demonstrated 4.307% inhibition of SARS-CoV-2 3CL-Pro protease activity at a concentration of 20 µM. These findings suggest that Chloroallyl methenamine chloride may have potential antiviral properties through multiple mechanisms..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (Quaternium-15 cis-form) is an antimicrobial agent used in cosmetics as a cosmetic preservative and antistatic agent.cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride is an oral teratogen, but not a dermal teratogen, and has been dosed in rats at doses exceeding the expected cumulative exposures for cosmetics.
SynonymsQuaternium-15 cis-form
Chemical Properties
Molecular Weight251.16
FormulaC9H16Cl2N4
Cas No.51229-78-8
Smiles[Cl-].Cl\C=C/C[N+]12CN3CN(CN(C3)C1)C2
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 7.5 mg/mL (29.86 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.98 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9815 mL19.9076 mL39.8153 mL199.0763 mL
5 mM0.7963 mL3.9815 mL7.9631 mL39.8153 mL
10 mM0.3982 mL1.9908 mL3.9815 mL19.9076 mL
20 mM0.1991 mL0.9954 mL1.9908 mL9.9538 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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