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Anti-MD1 Antibody (7H847) is a Rabbit antibody targeting MD1. Anti-MD1 Antibody (7H847) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $94 | 7-10 days | |
100 μL | $269 | 7-10 days |
Description | Anti-MD1 Antibody (7H847) is a Rabbit antibody targeting MD1. Anti-MD1 Antibody (7H847) can be used in ELISA. |
Alias | MMD-1, MD-1, MD1, lymphocyte antigen 86, dJ80N2.1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7H847 |
Reactivity | Mouse |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LY86 (rM LY86; TMPY-00878; Met 1-Ser 162; NP_034875.1). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | MD-1 and MD-2 are secretory glycoproteins that exist on the cell surface in complexes with transmembrane proteins. MD-1 is anchored by radioprotective 15 (RP15) which is a molecule containing leucine-rich repeats and is expressed on B cells, dendritic cells, and macrophages, while MD-2 is associated with TLR4. MD-1 is required for efficient RP15 cell surface expression and function. It is indicated that the RP15/MD1 complex, in conjunction with TLR4, mediates the innate immune response to LPS in B cells, and also plays a role in protecting against apoptosis, B-cell proliferation, etc. Mouse MD-1 cDNA encodes a 162 amino acid precursor protein with a putative 19 aa signal peptide and two potential N-linked glycosylation sites. It shares 4% and 66% amino acid sequence identity with chicken and human MD-1 respectively. MD-1 is mainly expressed in the spleen, and also detectable in the liver, brain, thymus, and kidney. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse LY86 protein (TMPY-00878) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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