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Tubeimoside I

Name: Tubeimoside I
Brand: TargetMol
SKU: T2715
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2715Cas No. 102040-03-9

Alias Tubeimoside-1, Lobatoside-H

Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).

Tubeimoside I

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Purity: 99.94%

Catalog No. T2715Alias Tubeimoside-1, Lobatoside-HCas No. 102040-03-9

Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$30	In Stock	In Stock
10 mg	$37	In Stock	In Stock
25 mg	$56	In Stock	In Stock
50 mg	$78	In Stock	In Stock
100 mg	$113	-	In Stock
200 mg	$163	-	In Stock
500 mg	$273	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.94%

Color:White

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COA HNMR LCMS

Product Introduction

Tubeimoside I AI Summary

Tubeimoside I exhibits a diverse range of bioactivities. It shows significant toxicity in ICR mice with an LD50 of 18.7 mg/kg. Additionally, it demonstrates antimigratory activity against HUVEC cells and substantial antiproliferative activity against various human cell lines, including A2780DDP, NCI-H1299, JEG3, EC109, T24, SKOV3, HepG2, HeLa, PGCL3, PC9, A549, NCI-H460, PC3, and DU145, with varying IC50 values observed at different time points. The compound is also cytotoxic against HeLa cells. Its pharmacokinetic profile reveals oral bioavailability, and includes parameters such as elimination half-life, clearance, volume of distribution, area under the curve (AUC), maximum concentration (Cmax), time to reach maximum concentration (Tmax), and mean residence time (MRT) in both rats and mice, highlighting its absorption, distribution, metabolism, and excretion characteristics..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).
Synonyms	Tubeimoside-1, Lobatoside-H

Chemical Properties

Molecular Weight	1319.43
Formula	C₆₃H₉₈O₂₉
Cas No.	102040-03-9
Smiles	CC1OC2OC3C(O)C(O)COC3OC(=O)C34CCC(C)(C)CC3C3=CCC5C6(C)CC(O)C(OC7OC(CO)C(O)C(O)C7OC7OCC(OC(=O)CC(C)(O)CC(=O)OC1C(OC1OCC(O)C(O)C1O)C2O)C(O)C7O)C(C)(CO)C6CCC5(C)C3(C)CC4
Relative Density.	1.5g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 255 mg/mL (193.27 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (1.52 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.7579 mL	3.7895 mL	7.5790 mL	37.8952 mL
5 mM	0.1516 mL	0.7579 mL	1.5158 mL	7.5790 mL
10 mM	0.0758 mL	0.3790 mL	0.7579 mL	3.7895 mL
20 mM	0.0379 mL	0.1895 mL	0.3790 mL	1.8948 mL
50 mM	0.0152 mL	0.0758 mL	0.1516 mL	0.7579 mL
100 mM	0.0076 mL	0.0379 mL	0.0758 mL	0.3790 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc