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Cyclo(Gly-His) is a cyclic dipeptide encompassed within liposomes, exhibiting antimicrobial and anticancer properties with cytotoxic effects on HeLa and MCF-7 cells, demonstrating IC50 values of 1.699 mM and 0.358 mM, respectively. This compound is relevant for drug delivery system research [1].

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| 5 mg | Inquiry | Inquiry | Inquiry | |
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| Description | Cyclo(Gly-His) is a cyclic dipeptide encompassed within liposomes, exhibiting antimicrobial and anticancer properties with cytotoxic effects on HeLa and MCF-7 cells, demonstrating IC50 values of 1.699 mM and 0.358 mM, respectively. This compound is relevant for drug delivery system research [1]. |
| In vitro | Cyclo(Gly-His) exhibits cytotoxicity toward HeLa and MCF-7 cells, with IC50 values of 1.699 mM and 0.358 mM, respectively [1]. |
| Molecular Weight | 194.19 |
| Formula | C8H10N4O2 |
| Cas No. | 15266-88-3 |
| Smiles | C([C@H]1C(=O)NCC(=O)N1)C2=CN=CN2 |
| Sequence | Cyclo(Gly-His) |
| Sequence Short | Cyclo(GH) |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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