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Anti-CCL2 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-Biotin can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
| Description | Anti-CCL2 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-Biotin can be used in ELISA,FCM. |
| Synonyms | Small-inducible cytokine A2, Monocyte secretory protein JE, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Monocyte chemoattractant protein 1, HC11, C-C motif chemokine 2 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of CCL2 overexpressed 446F cells with TMAZ-0376B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CCL2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:10587439, PubMed:9837883). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8195247, PubMed:8627182, PubMed:9792674). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690) |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | CCL2 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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