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WL47 TFA

Name: WL47 TFA
Brand: TargetMol
SKU: T78373
Price: 149 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T78373

Alias WL 47 TFA

WL47 TFA is a selective small molecule caveolin-1 oligomer disruptor that disrupts CAV1 oligomers.

WL47 TFA

🥰Excellent

Purity: 99.80%

Catalog No. T78373Alias WL 47 TFA

WL47 TFA is a selective small molecule caveolin-1 oligomer disruptor that disrupts CAV1 oligomers.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$149	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.80%

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COA

Product Introduction

Bioactivity

Description	WL47 TFA is a selective small molecule caveolin-1 oligomer disruptor that disrupts CAV1 oligomers.
Targets&IC50	caveolin-1 ligand:23 nM (Kd)
In vitro	WL47 TFA is a high-affinity caveolin-1 (CAV1) ligand (Kd=23 nM) that efficiently disrupts CAV1 oligomers. WL47 TFA exhibits higher selectivity for CAV1 compared to BSA, casein and HEWL. [1]
Synonyms	WL 47 TFA

Chemical Properties

Molecular Weight	1814.16
Formula	C₇₆H₁₁₉F₃N₂₂O₁₈S₄
Smiles	[H]N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@H](C(N[C@@H](CS)C(N[C@@H](CS)C(N[C@H](C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@@H](CCSC)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CCCNC(N)=N)=O)=O)=O)CO)=O)=O)=O)CO)=O)=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)CCCCN.O=C(O)C(F)(F)F
Sequence	Lys-Leu-Arg-Met-Trp-Ser-Cys-Cys-Ser-Trp-Met-Arg-Leu-Lys
Sequence Short	KLRMWSCCSWMRLK

Storage & Solubility Information

Storage

keep away from moisture,store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (22.05 mM), Sonication is recommended.

H2O: 20 mg/mL (11.02 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (1.1 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	0.5512 mL	2.7561 mL	5.5122 mL	27.5610 mL
5 mM	0.1102 mL	0.5512 mL	1.1024 mL	5.5122 mL
10 mM	0.0551 mL	0.2756 mL	0.5512 mL	2.7561 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.0276 mL	0.1378 mL	0.2756 mL	1.3780 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc