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Hexaflumuron

Name: Hexaflumuron
Brand: TargetMol
SKU: T5117
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5117Cas No. 86479-06-3

Hexaflumuron is a chitin synthesis inhibitor used to bait and eliminate termite colonies. Termites are unable to metabolize hexaflumuron and clearance is slow, resulting in up to 100% elimination. Hexaflumuron has also been tested for use with the raisin moth, cowpea weevil, and Asiatic rice borer with positive results.

Hexaflumuron

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Purity: 99.76%

Catalog No. T5117Cas No. 86479-06-3

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$40	In Stock	In Stock
100 mg	$68	In Stock	In Stock
500 mg	$156	In Stock	In Stock
1 g	$198	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.76%

Color:White

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COA HNMR LCMS

Product Introduction

Hexaflumuron AI Summary

Hexaflumuron exhibits a diverse bioactivity profile, functioning as both an antagonist and agonist in various signaling pathways. It acts as an antagonist of androgen receptor signaling (IC50: 35481.3 nM) and estrogen receptor alpha signaling (IC50: 8912.5 nM), while also serving as an agonist of the antioxidant response element (ARE) signaling pathway (IC50: 13685.4 nM) and an activator of the human pregnane X receptor (PXR) signaling pathway (IC50: 25118.9 nM). The compound further demonstrates significant larvicidal activity: 100.0% mortality against Culex pipiens pallens (mosquito) larvae at 0.25 mg/L after 8 days, and 80.0% mortality against Mythimna separata (Oriental armyworm) larvae at 10 mg/L on drug-pretreated corn leaves after 4 days. Additionally, it shows contact toxicity against Trichogramma nubilale (LC50: 9672.0 mgAi/L; LC95: 51197.0 mgAi/L), acute oral and contact toxicity against adult Anagrus nilaparvatae, and high toxicity in Daphnia magna (EC90: 0.5 ppb). The compound exhibits insecticidal effects against Plutella xylostella (diamondback moth) larvae, with an LC90 of 0.04 ppm and varying efficacy against fufenozide-resistant (LC50: 274.1 ug/mL) and susceptible (LC50: 9.56 ug/mL) strains, suggesting potential for insecticide applications with considerations for resistance management..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Chemical Properties

Molecular Weight	461.14
Formula	C₁₆H₈Cl₂F₆N₂O₃
Cas No.	86479-06-3
Smiles	FC(F)C(F)(F)Oc1c(Cl)cc(NC(=O)NC(=O)c2c(F)cccc2F)cc1Cl
Relative Density.	1.4069 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (130.11 mM), Sonication is recommended.

H2O: Insoluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1685 mL	10.8427 mL	21.6854 mL	108.4269 mL
5 mM	0.4337 mL	2.1685 mL	4.3371 mL	21.6854 mL
10 mM	0.2169 mL	1.0843 mL	2.1685 mL	10.8427 mL
20 mM	0.1084 mL	0.5421 mL	1.0843 mL	5.4213 mL
50 mM	0.0434 mL	0.2169 mL	0.4337 mL	2.1685 mL
100 mM	0.0217 mL	0.1084 mL	0.2169 mL	1.0843 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc