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V-0219

Name: V-0219
Brand: TargetMol
SKU: T60047
Price: 69 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60047Cas No. 878453-71-5

V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.

V-0219

🥰Excellent

Purity: 99.91%

Catalog No. T60047Cas No. 878453-71-5

V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.

Pack Size	Price	Availability	Quantity
1 mg	$69	In Stock

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Purity:99.91%

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Product Introduction

Bioactivity

Description

V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.

Chemical Properties

Molecular Weight	410.43
Formula	C₂₀H₂₅F₃N₄O₂
Cas No.	878453-71-5
Smiles	FC(F)(F)C=1C=CC(=CC1)C2=NOC(=N2)CN3CCCC(C3)CN4CCOCC4
Relative Density.	1.258 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120 mg/mL (292.38 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4365 mL	12.1823 mL	24.3647 mL	121.8235 mL
5 mM	0.4873 mL	2.4365 mL	4.8729 mL	24.3647 mL
10 mM	0.2436 mL	1.2182 mL	2.4365 mL	12.1823 mL
20 mM	0.1218 mL	0.6091 mL	1.2182 mL	6.0912 mL
50 mM	0.0487 mL	0.2436 mL	0.4873 mL	2.4365 mL
100 mM	0.0244 mL	0.1218 mL	0.2436 mL	1.2182 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc