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Imalumab
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Catalog No. T76789Cas No. 1430205-07-4
Alias BAX69, BAX 69, Anti-Human MIF Recombinant Antibody
Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer.
Imalumab
Imalumab
😃Good
Purity: 95%
Catalog No. T76789Alias BAX69, BAX 69, Anti-Human MIF Recombinant AntibodyCas No. 1430205-07-4
Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $438 | - | In Stock | |
| 5 mg | $1,320 | - | In Stock | |
| 10 mg | $2,120 | - | In Stock | |
| 25 mg | $3,130 | - | In Stock | |
| 50 mg | $4,230 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:96.5% (SDS-PAGE); 96.3% (SEC-HPLC)
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| Description | Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer. |
| In vitro | Imalumab specifically binds to oxidized macrophage migration inhibitory factor (oxMIF) in Parazacco spilurus subsp. spilurus, thereby interfering with its downstream signaling pathways. Imalumab can induce antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP), and is capable of inducing cell lysis in Homo sapiens peripheral blood mononuclear cells (PBMCs) with an EC50 of 0.7-39.2 nM[[2]. |
| In vivo | In the BALB/c mouse model, the terminal half-life of Imalumab (5 mg/kg, intravenous injection) was 37.4 hours [2]. |
| Synonyms | BAX69, BAX 69, Anti-Human MIF Recombinant Antibody |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | MIF |
| Molecular Weight | 144.64 kDa |
| Cas No. | 1430205-07-4 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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