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Imalumab
🥰Excellent
Catalog No. T76789Cas No. 1430205-07-4
Alias BAX69, BAX 69, Anti-Human MIF Recombinant Antibody
Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer.
Imalumab
Imalumab
🥰Excellent
Purity: 95%
Catalog No. T76789Alias BAX69, BAX 69, Anti-Human MIF Recombinant AntibodyCas No. 1430205-07-4
Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $438 | - | In Stock | |
| 5 mg | $1,320 | - | In Stock | |
| 10 mg | $2,120 | - | In Stock | |
| 25 mg | $3,130 | - | In Stock | |
| 50 mg | $4,230 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer. |
| In vitro | Imalumab specifically binds to oxidized macrophage migration inhibitory factor (oxMIF) in Parazacco spilurus subsp. spilurus, thereby interfering with its downstream signaling pathways. Imalumab can induce antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP), and is capable of inducing cell lysis in Homo sapiens peripheral blood mononuclear cells (PBMCs) with an EC50 of 0.7-39.2 nM[[2]. |
| In vivo | In the BALB/c mouse model, the terminal half-life of Imalumab (5 mg/kg, intravenous injection) was 37.4 hours [2]. |
| Synonyms | BAX69, BAX 69, Anti-Human MIF Recombinant Antibody |
| Cas No. | 1430205-07-4 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: buy Imalumab | purchase Imalumab | Imalumab cost | order Imalumab | Imalumab in vivo | Imalumab in vitro
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