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Casdozokitug
🥰Excellent
Catalog No. T80568Cas No. 2643331-37-5
Alias SRF-388, SRF388
Casdozokitug is an IgG1κ monoclonal antibody that selectively binds to interleukin-27 (IL-27) and functions as a first-in-class human anti-IL-27 research compound designed to inhibit the immunosuppressive activity of this cytokine. Casdozokitug demonstrates particular relevance in tumor types where IL-27 contributes to the establishment of an immunosuppressive tumor microenvironment and resistance to immune checkpoint inhibitor therapies, thereby offering a novel immunology research tool.
Casdozokitug
Casdozokitug
🥰Excellent
Purity: 95%
Catalog No. T80568Alias SRF-388, SRF388Cas No. 2643331-37-5
Casdozokitug is an IgG1κ monoclonal antibody that selectively binds to interleukin-27 (IL-27) and functions as a first-in-class human anti-IL-27 research compound designed to inhibit the immunosuppressive activity of this cytokine. Casdozokitug demonstrates particular relevance in tumor types where IL-27 contributes to the establishment of an immunosuppressive tumor microenvironment and resistance to immune checkpoint inhibitor therapies, thereby offering a novel immunology research tool.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $619 | - | In Stock | |
| 10 mg | $993 | - | In Stock | |
| 25 mg | $1,470 | - | In Stock | |
| 50 mg | $1,980 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:95%
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Casdozokitug is an IgG1κ monoclonal antibody that selectively binds to interleukin-27 (IL-27) and functions as a first-in-class human anti-IL-27 research compound designed to inhibit the immunosuppressive activity of this cytokine. Casdozokitug demonstrates particular relevance in tumor types where IL-27 contributes to the establishment of an immunosuppressive tumor microenvironment and resistance to immune checkpoint inhibitor therapies, thereby offering a novel immunology research tool. |
| Synonyms | SRF-388, SRF388 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Host Species | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID |
| Cas No. | 2643331-37-5 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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