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C24:1 3'-sulfo galactosylceramide (d18:1/24:1(15z))

Name: C24:1 3'-sulfo galactosylceramide (d18:1/24:1(15z))
Brand: TargetMol
SKU: T38285
Rating: 4.5 (1 reviews)

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Catalog No. T38285Cas No. 151057-28-2

Alias C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

C24:1 3'-sulfo galactosylceramide (d18:1/24:1(15z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like receptors to give the highest affinity for LMIR5. Galactosylceramide (d18:1/24:1(15Z)) induces MCP-1 production by basophils, which activates NFAT by increasing LMIR5, but not mast cells .C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) binds in vitro to CD1d binding and increased the proliferation of free mouse splenocytes.

C24:1 3'-sulfo galactosylceramide (d18:1/24:1(15z))

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Catalog No. T38285Alias C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))Cas No. 151057-28-2

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$1,760	Inquiry	Inquiry

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Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	C24:1 3'-sulfo galactosylceramide (d18:1/24:1(15z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like receptors to give the highest affinity for LMIR5. Galactosylceramide (d18:1/24:1(15Z)) induces MCP-1 production by basophils, which activates NFAT by increasing LMIR5, but not mast cells .C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) binds in vitro to CD1d binding and increased the proliferation of free mouse splenocytes.
In vitro	The relationship between structure and activity (SAR) of newly synthesized sulfatide isoforms C24:1 was evaluated. The basal IDO1 expression was significantly increased by C24:1 sulfatide (+87 ± 7% and +50 ± 5% at 1μΜ, respectively) over negative controls ; These effects functionally correlated with changes in IDO1 activity: l-kynurenine contents in the culture media were significantly increased by C24:1 sulfatide (+61 ± 8% and +48 ± 4% at 1μM, respectively) over negative controls.[2]
Synonyms	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Chemical Properties

Molecular Weight	890.3
Formula	C₄₈H₉₁NO₁₁S
Cas No.	151057-28-2
Smiles	O(C[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@H]1[C@H](O)[C@@H](OS(=O)(=O)O)[C@@H](O)[C@@H](CO)O1

Storage & Solubility Information

Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	Chloroform:Methanol (5:1): Soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Nuclear factor of activated Tcells (NFAT)MCP-1C24:1 3'-sulfo Galactosylceramide (d18:1/24:1)C24:1 3'sulfo Galactosylceramide (d18:1/24:1(15Z))C-24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))C24:1 3' sulfo Galactosylceramide (d18:1/24:1(15Z))

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