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NDSB-256

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Catalog No. TF0032Cas No. 81239-45-4
Alias NDSB256, 3-(Benzyldimethylammonio)propane-1-sulfonate

NDSB-256 (3-(Benzyldimethylammonio)propane-1-sulfonate) is a non-detergent sulfobetaine that prevents protein aggregation and increases the isomerization rate in a concentration-dependent manner.

NDSB-256

NDSB-256

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Purity: 99.56%
Catalog No. TF0032Alias NDSB256, 3-(Benzyldimethylammonio)propane-1-sulfonateCas No. 81239-45-4
NDSB-256 (3-(Benzyldimethylammonio)propane-1-sulfonate) is a non-detergent sulfobetaine that prevents protein aggregation and increases the isomerization rate in a concentration-dependent manner.
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1 g$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.56%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
NDSB-256 (3-(Benzyldimethylammonio)propane-1-sulfonate) is a non-detergent sulfobetaine that prevents protein aggregation and increases the isomerization rate in a concentration-dependent manner.
SynonymsNDSB256, 3-(Benzyldimethylammonio)propane-1-sulfonate
Chemical Properties
Molecular Weight257.35
FormulaC12H19NO3S
Cas No.81239-45-4
SmilesO=S(=O)([O-])CCC[N+](C)(C)CC=1C=CC=CC1
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 160 mg/mL (621.72 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM3.8858 mL19.4288 mL38.8576 mL194.2879 mL
5 mM0.7772 mL3.8858 mL7.7715 mL38.8576 mL
10 mM0.3886 mL1.9429 mL3.8858 mL19.4288 mL
20 mM0.1943 mL0.9714 mL1.9429 mL9.7144 mL
50 mM0.0777 mL0.3886 mL0.7772 mL3.8858 mL
100 mM0.0389 mL0.1943 mL0.3886 mL1.9429 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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