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C6 L-erythro Ceramide (d18:1/6:0)

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Catalog No. T36319Cas No. 189894-78-8
Alias C6 L-erythro Ceramide (d18:1/6:0)

C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).

C6 L-erythro Ceramide (d18:1/6:0)
Other Forms of C6 L-erythro Ceramide (d18:1/6:0):

C6 L-erythro Ceramide (d18:1/6:0)

😃Good
Catalog No. T36319Alias C6 L-erythro Ceramide (d18:1/6:0)Cas No. 189894-78-8
C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).
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1 mg$71835 days35 days
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Product Introduction

Bioactivity
Description
C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).
SynonymsC6 L-erythro Ceramide (d18:1/6:0)
Chemical Properties
Molecular Weight397.644
FormulaC24H47NO3
Cas No.189894-78-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: Soluble
Chloroform: Soluble
DMF: 5 mg/mL (12.57 mM), Sonication is recommended.
DMSO: Soluble
Solution Preparation Table
DMF
1mg5mg10mg50mg
1 mM2.5148 mL12.5741 mL25.1481 mL125.7406 mL
5 mM0.5030 mL2.5148 mL5.0296 mL25.1481 mL
10 mM0.2515 mL1.2574 mL2.5148 mL12.5741 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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Keywords

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