Cinnamtannin A2

Name: Cinnamtannin A2
Brand: TargetMol
SKU: T40977
Rating: 4.5 (1 reviews)

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Catalog No. T40977Cas No. 86631-38-1

Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity.

Cinnamtannin A2

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Catalog No. T40977Cas No. 86631-38-1

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$185	Backorder	Backorder
5 mg	$473	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity.
In vitro	Cinnamtannin A2 (0.125-2.0 μg/mL) exhibited concentration-dependent antioxidant activity by prolonging the lag time of LDL oxidation induced by copper ions or MeO-AMVN, but its effect was weaker than that of the monomers and other oligomers of Senegalia catechu camellia sinensis [3].
In vivo	Cinnamtannin A2 (10 mg/kg, i.p. for the period 30 days) ameliorates the altered level of creatinine, blood urea nitrogen (BUN), Neutrophil gelatinase-associated lipocalin (NGAL), Kidney Injury Molecule-1 (KIM-1), and cytokines in the serum and microalbuminurea in the urine of 5/6 nephrectomized rats [2].

Chemical Properties

Molecular Weight	1155.02
Formula	C₆₀H₅₀O₂₄
Cas No.	86631-38-1
Smiles	O[C@@H]1[C@H](C=2C(=C(C(O)=CC2O)[C@H]3C=4C(O[C@@H]([C@@H]3O)C5=CC(O)=C(O)C=C5)=CC(O)=CC4O)O[C@@H]1C6=CC(O)=C(O)C=C6)C7=C8C([C@@H]([C@@H](O)[C@H](O8)C9=CC(O)=C(O)C=C9)C%10=C%11C(C[C@@H](O)[C@H](O%11)C%12=CC(O)=C(O)C=C%12)=C(O)C=C%10O)=C(O)C=C7O
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage	keep away from moisture,store at low temperature,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	Ethanol: ≥ 40 mg/mL, Sonication is recommended.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

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