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Cinnamtannin A2
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Catalog No. T40977Cas No. 86631-38-1
Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity.
Cinnamtannin A2
Copy Product Info😃Good
Catalog No. T40977Cas No. 86631-38-1
Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $163 | Inquiry | Inquiry | |
| 2 mg | $243 | Inquiry | Inquiry | |
| 5 mg | $413 | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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| Description | Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity. |
| In vitro | Cinnamtannin A2 (0.125-2.0 μg/mL) exhibited concentration-dependent antioxidant activity by prolonging the lag time of LDL oxidation induced by copper ions or MeO-AMVN, but its effect was weaker than that of the monomers and other oligomers of Senegalia catechu camellia sinensis [3]. |
| In vivo | Cinnamtannin A2 (10 mg/kg, i.p. for the period 30 days) ameliorates the altered level of creatinine, blood urea nitrogen (BUN), Neutrophil gelatinase-associated lipocalin (NGAL), Kidney Injury Molecule-1 (KIM-1), and cytokines in the serum and microalbuminurea in the urine of 5/6 nephrectomized rats [2]. |
| Molecular Weight | 1155.02 |
| Formula | C60H50O24 |
| Cas No. | 86631-38-1 |
| Smiles | O[C@@H]1[C@H](C=2C(=C(C(O)=CC2O)[C@H]3C=4C(O[C@@H]([C@@H]3O)C5=CC(O)=C(O)C=C5)=CC(O)=CC4O)O[C@@H]1C6=CC(O)=C(O)C=C6)C7=C8C([C@@H]([C@@H](O)[C@H](O8)C9=CC(O)=C(O)C=C9)C%10=C%11C(C[C@@H](O)[C@H](O%11)C%12=CC(O)=C(O)C=C%12)=C(O)C=C%10O)=C(O)C=C7O |
| Relative Density. | no data available |
| Storage | keep away from moisture,store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol: ≥ 40 mg/mL, Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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