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Zalutumumab
Catalog No. T76721 Copy Product Info
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Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN).
Zalutumumab
Copy Product Info🥰Excellent
Catalog No. T76721
Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN).
Zalutumumab
Cas No. 667901-13-5
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $215 | - | In Stock | |
| 5 mg | $556 | - | In Stock | |
| 10 mg | $888 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.2% (SDS-PAGE); 98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN). |
| In vitro | Methods: A431 cell line was treated with zalutumumab (0-1 μM, 96 hours) and cell viability was measured. Results: Zalutumumab inhibited A431 cell proliferation with an IC50 value of 1.5 nM. [1] |
| In vivo | Zalutumumab (5 mg/kg, intraperitoneal injection 2 hours after tumor induction) can affect tumor growth in A431 xenograft model mice.[1] |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | ERBB1/EGFR/HER1 |
| Molecular Weight | 146.63 kDa |
| Cas No. | 667901-13-5 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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