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Zalutumumab

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Catalog No. T76721Cas No. 667901-13-5

Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN).

Zalutumumab

Zalutumumab

😃Good
Catalog No. T76721Cas No. 667901-13-5
Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$215-In Stock
5 mg$556-In Stock
10 mg$888-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.2% (SDS-PAGE); 98.4% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN).
In vitro
Methods: A431 cell line was treated with zalutumumab (0-1 μM, 96 hours) and cell viability was measured.
Results: Zalutumumab inhibited A431 cell proliferation with an IC50 value of 1.5 nM. [1]
In vivo
Zalutumumab (5 mg/kg, intraperitoneal injection 2 hours after tumor induction) can affect tumor growth in A431 xenograft model mice.[1]
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetERBB1/EGFR/HER1
Chemical Properties
Molecular Weight146.63 kDa
Cas No.667901-13-5
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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