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Zalutumumab
🥰Excellent
Catalog No. T76721Cas No. 667901-13-5
Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN).
Zalutumumab
Zalutumumab
🥰Excellent
Purity: 95%
Catalog No. T76721Cas No. 667901-13-5
Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $215 | In Stock | |
| 5 mg | $556 | In Stock | |
| 10 mg | $888 | In Stock |
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Concentration:5.57 mg/mL
Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Zalutumumab is a high-affinity fully human monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) and is used to treat squamous cell carcinoma of the head and neck (SCCHN). |
| In vitro | Methods: A431 cell line was treated with zalutumumab (0-1 μM, 96 hours) and cell viability was measured. Results: Zalutumumab inhibited A431 cell proliferation with an IC50 value of 1.5 nM. [1] |
| In vivo | Zalutumumab (5 mg/kg, intraperitoneal injection 2 hours after tumor induction) can affect tumor growth in A431 xenograft model mice.[1] |
| Cas No. | 667901-13-5 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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