Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ERD-3111 (Compound 44), an orally active PROTAC ERα degrader (DC50: 0.5 nM), exhibits efficacy in inhibiting tumor growth in both the parental MCF-7 xenograft model harboring wild-type ER and two ESR1-mutated mouse models. This compound has utility in the investigation of ER+ breast cancer [1].
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Description | ERD-3111 (Compound 44), an orally active PROTAC ERα degrader (DC50: 0.5 nM), exhibits efficacy in inhibiting tumor growth in both the parental MCF-7 xenograft model harboring wild-type ER and two ESR1-mutated mouse models. This compound has utility in the investigation of ER+ breast cancer [1]. |
Molecular Weight | 854.89 |
Formula | C45H46F4N8O5 |
CAS No. | 2832865-25-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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ERD-3111 2832865-25-3 Endocrinology/Hormones Estrogen Receptor/ERR inhibitor inhibit