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2'-O-Methyladenosine

Name: 2'-O-Methyladenosine
Brand: TargetMol
SKU: T13482
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13482Cas No. 2140-79-6

2'-O-Methyladenosine, a methylated adenine residue, is present in the urine of both normal individuals and patients with adenosine deaminase deficiency, and exhibits unique hypotensive activities.

2'-O-Methyladenosine

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Purity: 99.89%

Catalog No. T13482Cas No. 2140-79-6

2'-O-Methyladenosine, a methylated adenine residue, is present in the urine of both normal individuals and patients with adenosine deaminase deficiency, and exhibits unique hypotensive activities.

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$45	In Stock
25 mg	$59	In Stock
50 mg	$72	In Stock
100 mg	$112	In Stock
200 mg	$163	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Purity:99.89%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	2'-O-Methyladenosine, a methylated adenine residue, is present in the urine of both normal individuals and patients with adenosine deaminase deficiency, and exhibits unique hypotensive activities.
In vivo	2'-O-Methyladenosine (100, 200 mg/kg, i.p., single dose) demonstrates distinct hypotensive effects in rats [2].
Animal Research	Animal Model: Male spontaneously hypertensive rats (SHR; 16 weeks old). Dosage: 100, 200 mg/kg. Administration: I.P., single dose.[2]

Chemical Properties

Molecular Weight	281.27
Formula	C₁₁H₁₅N₅O₄
Cas No.	2140-79-6
Smiles	CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12
Relative Density.	1.84g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/ml (195.54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5553 mL	17.7765 mL	35.5530 mL	177.7651 mL
5 mM	0.7111 mL	3.5553 mL	7.1106 mL	35.5530 mL
10 mM	0.3555 mL	1.7777 mL	3.5553 mL	17.7765 mL
20 mM	0.1778 mL	0.8888 mL	1.7777 mL	8.8883 mL
50 mM	0.0711 mL	0.3555 mL	0.7111 mL	3.5553 mL
100 mM	0.0356 mL	0.1778 mL	0.3555 mL	1.7777 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc