Shopping Cart
Remove All
Your shopping cart is currently empty
Trevogrumab
😃Good
Catalog No. T80951Cas No. 1429201-24-0
Alias REGN-1033, REGN1033
Trevogrumab (REGN-1033) is a fully human monoclonal antibody specifically designed to target and inhibit the activity of growth differentiation factor 8 (GDF8), which is also known as myostatin and functions as a negative regulator of muscle growth;Trevogrumab is currently under extensive research of sarcopenia, a complex condition characterized by progressive and generalized loss of skeletal muscle mass and function often associated with aging, wasting atrophy, various chronic diseases, and significant alterations in dietary and nutritional intake.
Trevogrumab
Trevogrumab
😃Good
Purity: 95%
Catalog No. T80951Alias REGN-1033, REGN1033Cas No. 1429201-24-0
Trevogrumab (REGN-1033) is a fully human monoclonal antibody specifically designed to target and inhibit the activity of growth differentiation factor 8 (GDF8), which is also known as myostatin and functions as a negative regulator of muscle growth;Trevogrumab is currently under extensive research of sarcopenia, a complex condition characterized by progressive and generalized loss of skeletal muscle mass and function often associated with aging, wasting atrophy, various chronic diseases, and significant alterations in dietary and nutritional intake.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $415 | - | In Stock | |
| 5 mg | $1,230 | - | In Stock | |
| 10 mg | $1,650 | - | In Stock | |
| 25 mg | $2,450 | - | In Stock | |
| 50 mg | $3,290 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:97.6% (SDS-PAGE); 95.9% (SEC-HPLC)
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Trevogrumab (REGN-1033) is a fully human monoclonal antibody specifically designed to target and inhibit the activity of growth differentiation factor 8 (GDF8), which is also known as myostatin and functions as a negative regulator of muscle growth;Trevogrumab is currently under extensive research of sarcopenia, a complex condition characterized by progressive and generalized loss of skeletal muscle mass and function often associated with aging, wasting atrophy, various chronic diseases, and significant alterations in dietary and nutritional intake. |
| In vitro | Human skeletal myoblasts were treated with Trevogrumab (40 nM, 30 minutes), and the target protein levels were detected by Western Blot. Results: Trevogrumab effectively inhibited myostatin-induced Smad2/3 activation, showing high affinity and specificity. [1] |
| In vivo | Trevogrumab (0.1-30 mg/kg, subcutaneously, twice a week for 4 weeks) treated mice resulted in a significant increase in gastrocnemius (GA) and tibialis anterior (TA) muscle weight (~20%) and an increase in myofiber area (~15%).[1] |
| Synonyms | REGN-1033, REGN1033 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | GDF8/Myostatin |
| Molecular Weight | 144.02 kDa |
| Cas No. | 1429201-24-0 |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Trevogrumab | purchase Trevogrumab | Trevogrumab cost | order Trevogrumab | Trevogrumab in vivo | Trevogrumab in vitro | Trevogrumab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.