Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SS47, a PROTAC -based HPK1 degrader , exerts proteasome-mediated HPK1 degradation. The degradation of HPK1 via SS47 also significantly enhances the?in?vivo?antitumor efficacy of BCMA CAR-T cell research. HPK1, an?immunosuppressive?regulatory kinase, is a promising target for cancer immunotherapies [1] .
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Description | SS47, a PROTAC -based HPK1 degrader , exerts proteasome-mediated HPK1 degradation. The degradation of HPK1 via SS47 also significantly enhances the?in?vivo?antitumor efficacy of BCMA CAR-T cell research. HPK1, an?immunosuppressive?regulatory kinase, is a promising target for cancer immunotherapies [1] . |
Molecular Weight | 953.07 |
Formula | C49H56N6O12S |
CAS No. | 2636072-62-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SS47 2636072-62-1 inhibitor inhibit