Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

FDGlcU

Name: FDGlcU
Brand: TargetMol
SKU: T86414
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T86414Cas No. 209540-67-0

FDGlcU is a fluorescent probe used for non-invasive imaging, demonstrating high fluorescent activity. When conjugated with two mono-glucuronides, it is non-fluorescent (Ex/Em=480/514 nm) [1].

FDGlcU

😃Good

Catalog No. T86414Cas No. 209540-67-0

FDGlcU is a fluorescent probe used for non-invasive imaging, demonstrating high fluorescent activity. When conjugated with two mono-glucuronides, it is non-fluorescent (Ex/Em=480/514 nm) [1].

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	Inquiry	3-6 months	3-6 months
50 mg	Inquiry	3-6 months	3-6 months
100 mg	Inquiry	3-6 months	3-6 months

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Resource Download

Product Introduction

Bioactivity

Description	FDGlcU is a fluorescent probe used for non-invasive imaging, demonstrating high fluorescent activity. When conjugated with two mono-glucuronides, it is non-fluorescent (Ex/Em=480/514 nm) [1].
In vitro	FDGlcU, at a concentration of 0.5 μg/mL over 12 hours, demonstrates enzymatic activity and inhibits βG activity in live bacteria [1].
In vivo	FDGlcU (7.3 μM/kg) is used for in vivo time-lapse imaging of bacterial βG activity [1]. For whole-body imaging of intestinal βG activity [1], administer 50 μL of DDW, FDGlcU (7.3 μM/kg), and fluorescein (7.3 μM/kg) via gavage on the day of imaging. Anesthetize the mice with isoflurane and perform whole-body optical imaging using an IVIS spectrum optical imaging system with a GFP filter set. In a biodistribution study, sacrifice the mice 3 hours after gavage with FDGlcU or fluorescein (λex = 480 nm, λem = 514 nm). This protocol should be modified according to specific needs.

Chemical Properties

Molecular Weight	893.63
Formula	C₃₉H₂₈F₅NO₁₈
Cas No.	209540-67-0
Smiles	O=C1OC2(C=3C1=CC(NC(=O)C4=C(F)C(F)=C(F)C(F)=C4F)=CC3)C=5C(OC=6C2=CC=C(O[C@@H]7O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]7O)C6)=CC(O[C@@H]8O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]8O)=CC5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc