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Fucosterol

Name: Fucosterol
Brand: TargetMol
SKU: T8184
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8184Cas No. 17605-67-3

Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.

Fucosterol

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Purity: 99.68%

Catalog No. T8184Cas No. 17605-67-3

Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$76	In Stock
10 mg	$118	In Stock
25 mg	$238	In Stock
50 mg	$356	In Stock
100 mg	$528	In Stock
500 mg	$1,150	Backorder

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Purity:99.68%

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Product Introduction

Bioactivity

Description	Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.
In vitro	Fucosterol (0-50 μM; 7 days) suppresses the expression of PPARα and C/EBPα in fully differentiated control adipocytes [1], shows cytotoxicity against T47D and HT29 cell lines (IC50s: 27.94 and 70.41 μg/ml) [3], and decreases the proliferation of HEK293, MCF-7, and SiHa cells (IC50s: 185.4, 43.3, and 34.0 μg/ml) [4].
In vivo	Fucosterol (p.o.; 30mg/kg) causes a significant decrease in serum glucose concentrations and exhibits inhibition of sorbitol accumulations in the lenses [2].
Cell Research	Cell Line: 3T3-L1 adipocytes. Concentration: 0 μM; 25 μM; 50 μM. Incubation Time: 7 days [1]

Chemical Properties

Molecular Weight	412.69
Formula	C₂₉H₄₈O
Cas No.	17605-67-3
Smiles	[H][C@@]12CC[C@H]([C@H](C)CC\C(=C\C)C(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2CC(O)CC[C@]12C
Relative Density.	0.98 g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 16.67 mg/mL (40.39 mM), Sonication is recommended.

Solution Preparation Table

Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.4231 mL	12.1156 mL	24.2313 mL	121.1563 mL
5 mM	0.4846 mL	2.4231 mL	4.8463 mL	24.2313 mL
10 mM	0.2423 mL	1.2116 mL	2.4231 mL	12.1156 mL
20 mM	0.1212 mL	0.6058 mL	1.2116 mL	6.0578 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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