Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

mTOR kinase Inhibitor 2

🥰Excellent
Catalog No. T9315Cas No. 1021917-65-6

2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- is a potent mTOR inhibitor with IC50 of 0.176 μM and >30 μM for mTOR and PI3Kα, respectively.

mTOR kinase Inhibitor 2

mTOR kinase Inhibitor 2

🥰Excellent
Purity: 99.97%
Catalog No. T9315Cas No. 1021917-65-6
2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- is a potent mTOR inhibitor with IC50 of 0.176 μM and >30 μM for mTOR and PI3Kα, respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$89In StockIn Stock
5 mg$202In StockIn Stock
10 mg$298In StockIn Stock
25 mg$476In StockIn Stock
50 mg$678In StockIn Stock
100 mg$912In StockIn Stock
1 mL x 10 mM (in DMSO)$217In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.97%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- is a potent mTOR inhibitor with IC50 of 0.176 μM and >30 μM for mTOR and PI3Kα, respectively.
Chemical Properties
Molecular Weight369.42
FormulaC19H23N5O3
Cas No.1021917-65-6
SmilesC(N1C=2C(NC1=O)=NC=C(N2)C=3C=CC(C(C)(C)O)=NC3)C4CCOCC4
Relative Density.1.292 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (135.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7069 mL13.5347 mL27.0695 mL135.3473 mL
5 mM0.5414 mL2.7069 mL5.4139 mL27.0695 mL
10 mM0.2707 mL1.3535 mL2.7069 mL13.5347 mL
20 mM0.1353 mL0.6767 mL1.3535 mL6.7674 mL
50 mM0.0541 mL0.2707 mL0.5414 mL2.7069 mL
100 mM0.0271 mL0.1353 mL0.2707 mL1.3535 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

2H​Imidazo[4,​5​b]​pyrazin​2​one, 1,​3​dihydro​6​[6​(1​hydroxy​1​methylethyl)​​3​pyridinyl]​​1​[(tetrahydro​2H​pyran​4​yl)​methyl]​2H ​Imidazo[4,​5 ​b]​pyrazin ​2 ​one, 1,​3 ​dihydro ​6 ​[6 ​(1 ​hydroxy ​1 ​methylethyl)​ ​3 ​pyridinyl]​ ​1 ​[(tetrahydro ​2H ​pyran ​4 ​yl)​methyl]​
Related Tags: buy mTOR kinase Inhibitor 2 | purchase mTOR kinase Inhibitor 2 | mTOR kinase Inhibitor 2 cost | order mTOR kinase Inhibitor 2 | mTOR kinase Inhibitor 2 chemical structure | mTOR kinase Inhibitor 2 formula | mTOR kinase Inhibitor 2 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.