Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1].
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Description | Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1]. |
In vitro | Anticancer agent 101 (compound 2m; 24 and 48 h) exhibited antitumor activity, with IC50 values of 20.5 μM for Colo-205 cells and 62.9 μM for HepG2 cells [1]. At concentrations of 25 µM and 50 µM over 24 hours, Anticancer agent 101 decreased the expression of apoptotic proteins PI3K and FoXO3a, while upregulating the levels of PTEN and FoXO1 in Colo-205 cells. |
Molecular Weight | 363.38 |
Formula | C19H20F3N3O |
CAS No. | 2914922-80-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Anticancer agent 101 2914922-80-6 inhibitor inhibit