Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Raf inhibitor 1 dihydrochloride

😃Good
Catalog No. T4167Cas No. 1191385-19-9
Alias B-Raf inhibitor 1 dihydrochloride

Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.

Raf inhibitor 1 dihydrochloride

Raf inhibitor 1 dihydrochloride

😃Good
Purity: 99.54%
Catalog No. T4167Alias B-Raf inhibitor 1 dihydrochlorideCas No. 1191385-19-9
Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$42In StockIn Stock
2 mg$58In StockIn Stock
5 mg$105In StockIn Stock
10 mg$189In StockIn Stock
25 mg$316In StockIn Stock
50 mg$469In StockIn Stock
100 mg$687In StockIn Stock
500 mg$1,450-In Stock
1 mL x 10 mM (in DMSO)$198In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.54%
Appearance:Solid
Color:Yellow
Contact us for more batch information

Resource Download

Product Introduction

Bioactivity
Description
Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.
Targets&IC50
C-Raf:0.3 nM (Ki), B-Raf:1 nM (Ki), B-Raf (V600E):1 nM (Ki)
SynonymsB-Raf inhibitor 1 dihydrochloride
Chemical Properties
Molecular Weight551.86
FormulaC26H19ClN8.1:2HCl
Cas No.1191385-19-9
SmilesCl.Cl.Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Nc1ncccc1-c1ncnc2[nH]cnc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (18.12 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8121 mL9.0603 mL18.1205 mL90.6027 mL
5 mM0.3624 mL1.8121 mL3.6241 mL18.1205 mL
10 mM0.1812 mL0.9060 mL1.8121 mL9.0603 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Raf inhibitor 1 dihydrochloride | purchase Raf inhibitor 1 dihydrochloride | Raf inhibitor 1 dihydrochloride cost | order Raf inhibitor 1 dihydrochloride | Raf inhibitor 1 dihydrochloride chemical structure | Raf inhibitor 1 dihydrochloride formula | Raf inhibitor 1 dihydrochloride molecular weight