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Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that combines the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of DM1, a microtubule-inhibitory derivative of maytansine, and is utilized in the investigation of advanced breast cancer[1][2].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $597 | - | In Stock | |
| 5 mg | $1,320 | - | In Stock | |
| 10 mg | $2,150 | - | In Stock | |
| 25 mg | $3,190 | - | In Stock | |
| 50 mg | $4,280 | - | In Stock |
| Description | Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that combines the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of DM1, a microtubule-inhibitory derivative of maytansine, and is utilized in the investigation of advanced breast cancer[1][2]. |
| In vitro | Trastuzumab emtansine (2 μg/mL; 3 d) markedly inhibits the proliferation of epithelial ovarian cancer (EOC) cells[2]. |
| In vivo | Trastuzumab emtansine (15 mg/kg; i.v., three to five times weekly for 3 weeks) demonstrates significant anti-tumor effects in CB-17/SCID mice (6 weeks) injected with OVA10 cells[2]. |
| Synonyms | T-DM1 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | < 1.0 EU/mg |
| Uniprot ID | |
| Target | HER2 |
| Formula | N/A |
| Cas No. | 1018448-65-1 |
| Smiles | [Trastuzumab emtansine] |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | IgG1 |
| Storage | keep away from direct sunlight | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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