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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

[Sar1, Ile8]-Angiotensin II acetate

🥰Excellent
Catalog No. T7575L1

[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascular smooth muscle, including contra

[Sar1, Ile8]-Angiotensin II acetate
Other Forms of [Sar1, Ile8]-Angiotensin II acetate:

[Sar1, Ile8]-Angiotensin II acetate

🥰Excellent
Purity: 99.36%
Catalog No. T7575L1
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascular smooth muscle, including contra
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$41In Stock
10 mg$58In Stock
25 mg$128In Stock
50 mg$213In Stock
100 mg$320In Stock
200 mg$462In Stock
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Batch Information

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Purity:99.36%
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COA MS HPLC

Product Introduction

Bioactivity
Description
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascular smooth muscle, including contra
Chemical Properties
Molecular Weight1028.2
FormulaC48H77N13O12
SmilesCC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC)=O)CCC/N=C(N)\N)=O)C(C)C)=O)CC1=CC=C(O)C=C1)=O)C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(O)=O)[C@H](CC)C)=O)=O)CC3=CN=CN3)=O)C.CC(O)=O
ColorWhite
AppearanceSolid
SequenceSar-Arg-Val-Tyr-Ile-His-Pro-Ile
Sequence ShortGRVYIHPI
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10.28 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.9726 mL4.8629 mL9.7257 mL48.6287 mL
5 mM0.1945 mL0.9726 mL1.9451 mL9.7257 mL
10 mM0.0973 mL0.4863 mL0.9726 mL4.8629 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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