Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TASK-1-IN-1 is a potent and selective inhibitor of TASK-1 (Potassium Channel) (IC50: 148 nM).TASK-1-IN-1 has a reduced inhibitory effect on the TASK-3 channel with an IC50 of 1750 nM.TASK-1-IN-1 has anticancer effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 289.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 672.00 | |
500 mg | In stock | $ 1,430.00 |
Description | TASK-1-IN-1 is a potent and selective inhibitor of TASK-1 (Potassium Channel) (IC50: 148 nM).TASK-1-IN-1 has a reduced inhibitory effect on the TASK-3 channel with an IC50 of 1750 nM.TASK-1-IN-1 has anticancer effects. |
Targets&IC50 | TASK3:1750 nM, TASK1:148 nM |
In vitro | TASK-1-IN-1 (compound F3) exhibits inhibitory effects on cell proliferation and viability in the MCF-7 cancer cell line. However, these effects are not observed in TASK-1 knockdown MCF-7 cells, suggesting its specific action on TASK-1 channels.[1] |
Molecular Weight | 344.41 |
Formula | C22H20N2O2 |
CAS No. | 600125-11-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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TASK-1-IN-1 600125-11-9 Membrane transporter/Ion channel Potassium Channel TASK1IN1 inhibitor inhibit