Shopping Cart

Your shopping cart is currently empty

Methyltetrazine-Maleimide

Name: Methyltetrazine-Maleimide
Brand: TargetMol
SKU: T87768
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T87768

Methyltetrazine-Maleimide is a degradable ADC linker suitable for ADC synthesis. It contains a Tetrazine group capable of click chemistry reactions with TCO-containing groups.

Methyltetrazine-Maleimide

😃Good

Purity: 99.94%

Catalog No. T87768

Methyltetrazine-Maleimide is a degradable ADC linker suitable for ADC synthesis. It contains a Tetrazine group capable of click chemistry reactions with TCO-containing groups.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$64	-	In Stock
5 mg	$156	-	In Stock
10 mg	$248	-	In Stock
25 mg	$425	-	In Stock
50 mg	$617	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.94%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Methyltetrazine-Maleimide is a degradable ADC linker suitable for ADC synthesis. It contains a Tetrazine group capable of click chemistry reactions with TCO-containing groups.

Chemical Properties

Molecular Weight	352.35
Formula	C₁₇H₁₆N₆O₃
Smiles	CC1=NN=C(N=N1)C2=CC=C(C=C2)CNC(=O)CCN3C(=O)C=CC3=O
Color	Purple
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (227.05 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8381 mL	14.1904 mL	28.3809 mL	141.9044 mL
5 mM	0.5676 mL	2.8381 mL	5.6762 mL	28.3809 mL
10 mM	0.2838 mL	1.4190 mL	2.8381 mL	14.1904 mL
20 mM	0.1419 mL	0.7095 mL	1.4190 mL	7.0952 mL
50 mM	0.0568 mL	0.2838 mL	0.5676 mL	2.8381 mL
100 mM	0.0284 mL	0.1419 mL	0.2838 mL	1.4190 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc