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D-Ala-Lys-AMCA hydrochloride

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Catalog No. T18957Cas No. 2703746-41-0

D-Ala-Lys-AMCA hydrochloride, a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1), emits blue fluorescence and may be transported into Caco-2 cells and liver cancer cells.

D-Ala-Lys-AMCA hydrochloride

D-Ala-Lys-AMCA hydrochloride

😃Good
Purity: 98.83%
Catalog No. T18957Cas No. 2703746-41-0
D-Ala-Lys-AMCA hydrochloride, a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1), emits blue fluorescence and may be transported into Caco-2 cells and liver cancer cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$125In StockIn Stock
5 mg$313In StockIn Stock
10 mg$538-In Stock
25 mg$873-In Stock
50 mg$1,180InquiryInquiry
1 mL x 10 mM (in DMSO)$323-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.83%
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Product Introduction

Bioactivity
Description
D-Ala-Lys-AMCA hydrochloride, a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1), emits blue fluorescence and may be transported into Caco-2 cells and liver cancer cells.
Chemical Properties
Molecular Weight468.93
FormulaC21H29ClN4O6
Cas No.2703746-41-0
SmilesNC1=CC=C(C(C)=C(CC(NCCCC[C@H](NC([C@@H](C)N)=O)C(O)=O)=O)C(O2)=O)C2=C1.[H]Cl
Relative Density.1.31g/cm3
ColorYellow
AppearanceViscous
Storage & Solubility Information
Storagekeep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (213.25 mM), Sonication is recommended.
DMSO: 100 mg/mL (213.25 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (8.53 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.1325 mL10.6626 mL21.3251 mL106.6257 mL
5 mM0.4265 mL2.1325 mL4.2650 mL21.3251 mL
10 mM0.2133 mL1.0663 mL2.1325 mL10.6626 mL
20 mM0.1066 mL0.5331 mL1.0663 mL5.3313 mL
50 mM0.0427 mL0.2133 mL0.4265 mL2.1325 mL
100 mM0.0213 mL0.1066 mL0.2133 mL1.0663 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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