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Anti-REG3B Antibody (8S567) is a Rabbit antibody targeting REG3B. Anti-REG3B Antibody (8S567) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Antibody Type: Rabbit Monoclonal Application: WB Reactivity: Mouse |
Alias | REG-III, PAP1, Pap, HIP |
Ig Type | Rabbit IgG |
Clone | 8S567 |
Reactivity | Mouse |
Verified Activity | Anti-REG3B rabbit monoclonal antibody at 1:500 dilution. -Lane A: Mouse pancreas tissue lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:19 kDa. -Observed band size:17 kDa |
Application | WB |
Recommended Dose | WB: 1:500-1:2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse REG3B (rM REG3B; TMPY-03673; NP_035166.1; Met1-Gly175). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its expression level in colorectal tumors correlated inversely with pSTAT3 level and survival times of patients. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells. This pathway might be targeted in patients with colitis to reduce carcinogenesis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Mouse REG3B Protein (TMPY-03673) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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